AB076. Standardization and individualization in controlled ovarian stimulation

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2015;4(S1) www.amepc.org/tau dehydrogenase (SDH) activity, sperm mitochondrial membrane potential (MMP) and sperm adenosine triphosphate (ATP) content. The independent t-test and one-way repeated measures analysis of variance (ANOVA) were used to compare the variables between and within two groups. Results: In the indomethacin group, the percentage of progressive motile sperms, total motility, sperm MMP and ATP content were increased significantly after 3 months treatment (P<0.05). In the TAM group, total sperm count, sperm concentration, the percentage of progressive motile sperms, total motility, serum and seminal plasma TAC, sperm MMP and ATP content were significantly improved or increased (P<0.05), while spermatozoa intracellular ROS was significantly decreased (P<0.05). Compared to the indomethacin group, TAM treatment showed better improvement in total sperm count, sperm concentration, serum TAC, seminal plasma TAC, spermatozoa intracellular ROS and sperm SDH activity. Conclusions: TAM treatment can significantly improve sperm quality, which is achieved through alleviating oxidat ive stress , improving sperm mitochondrial functionality, and subsequently increasing sperm motility.